Study on quality standard for Guijiu / 中成药

AIM: To establish the quality standard of Guijiu(Rhizome or root of Podophyllum emodi(Wall.) Ying,Dysosma versipellis(Hance) M.Cheng or Dysosma pleiantha(Hance) Woodson.which herbs contained lignans including podophyllotoxin. METHODS: The microscopic examination, physio-chemical method such as LC-MS had been used. RESULTS: These methods can be used for the identification and quantitative analysis of Guijiu. CONCLUSION: The method proposes microscopic examination technique and physio-chemical method such as LC-MS fingerprint and LC-MS-MS for the identification and quantitative analysis of the herbs.